The Bloom Bugle

BLOOM MONTANA
Date
ISSUE 002

A few weeks ago I was searching on Google: What is— and the first question that came up was "What is CBD and does it really work?"

So here we are, I figured with stress and tension a constant in most people’s lives, CBD is going to be one of the options people are turning to. And I, like everyone else, need answers.


What is CBD? 

CBD (cannabidiol) is a therapeutic compound produced by cannabis. It is commonly extracted and processed into oils, gummies, topicals, and other products that have no doubt sparked your curiosity. And with curiosity comes a load of questions.

Cannabinoids are a class of compounds that interact with receptors throughout your body. CBD is just one of dozens of cannabinoids found in cannabis, including tetrahydrocannabinol (THC), which is the one responsible for marijuana’s famous high. Medical cannabis is technically any cannabis product used for medicinal purposes, and these can contain THC or CBD or both, said Nick Jikomes, a neuroscientist at Leafly, a website that provides information about legal cannabis. “A common mistake people make is to think that CBD is ‘the medical cannabinoid’ and THC is ‘the recreational cannabinoid.’” That’s inaccurate, he said, because THC is a potent anti-inflammatory and can be helpful for pain.


How does it actually work?

Each of our bodies has a set of receptors that interacts with cannabis compounds called cannabinoids, like CBD. These receptors, found throughout the body, comprise the endocannabinoid system (ECS), a complex signaling system that ensures our bodies maintain homeostasis. 

Put another way, the endocannabinoid system keeps us in balance by directing the communication traffic in our bodies. Cannabinoids such as CBD interact with this system, mimicking natural compounds (called endocannabinoids) produced by the body.

In the human body, CBD influences cannabinoid receptor activity and encourages production of the body’s natural endocannabinoids. Interestingly, CBD also affects activity beyond the endocannabinoid system and can also interact with opioid, dopamine, and serotonin receptors. The ability of CBD to interact with so many different systems throughout the body suggests it has the potential to open new frontiers in psychiatry and medicine.

Last year, the National Academies of Sciences, Engineering and Medicine released a nearly 500-page report on the health effects of cannabis and cannabinoids. A committee of 16 experts from a variety of scientific and medical fields analyzed the available evidence — more than 10,000 scientific abstracts in all. Because so few studies examine the effects of CBD on its own, the panel did not issue any findings about CBD specifically, but it did reach some conclusions about cannabis and cannabinoids more generally. The researchers determined that there is “conclusive or substantial evidence” supporting the use of cannabis or cannabinoids for chronic pain in adults, multiple sclerosis-related spasticity (a kind of stiffness and muscle spasms), and chemotherapy-induced nausea and vomiting. The committee also found “moderate” evidence that cannabis or cannabinoids can reduce sleep disturbances in people with obstructive sleep apnea, fibromyalgia, chronic pain and multiple sclerosis, as well as “limited” evidence that these substances can improve symptoms of Tourette’s syndrome, increase appetite and stem weight loss in people with HIV/AIDs, and improve symptoms of PTSD and anxiety.


What are some things to Consider when buying CBD?

Exactly where the CBD comes from is important, too. CBD products in the medical and adult-use cannabis markets come from plants bred for strong effects, aromas, and flavors. They often contain THC, cannabis’ main active ingredient, which causes euphoria. By contrast, hemp-derived CBD comes from industrial hemp plants consisting of less than 0.3% THC.

When talking about hemp, we’re referring to the low-resin industrial crop commonly used to make clothing, textiles, food, and other materials. And in this context, we’re using the word cannabis to describe the high-resin plants that are grown specifically for medical consumption or enjoyment.

Is one source better than the other? Here’s a glance at the pros and cons of each.

Hemp-derived CBD:

  • Pro: Hemp is legal federally in the US (but check your local laws to ensure it’s legal in your state), and hemp-derived CBD products are widely available for purchase online and in grocery and drug stores.
  • Pro: Hemp produces only trace levels of THC, making it appealing for consumers wanting to avoid THC altogether.
  • Con: Hemp produces a limited spectrum of therapeutic compounds compared to high-resin cannabis. 
  • Con: Hemp products are currently unregulated, leaving unreliable potencies, dubious claims, and questionable ingredients unchecked.


Cannabis-derived CBD:

  • Pro: Cannabis produces a wider spectrum of therapeutic compounds (and in greater abundance) compared to hemp. 
  • Pro: Cannabis-derived CBD products are strictly regulated and tested per state laws.
  • Con: Cannabis-derived CBD is only available in states with legal cannabis, making it unavailable to consumers outside legal states.


Other important pieces of jargon include “full spectrum” and “broad spectrum,” versus “CBD isolate.”

  • Full spectrum CBD includes trace levels of other cannabinoids and terpenes, including THC.
  • Broad spectrum CBD includes trace levels of other cannabinoids and terpenes, but no THC.
  • CBD isolate consists of nearly pure CBD crystals with no other cannabinoids and terpenes.


No overarching federal authority polices the use of these terms, unlike, for example, the USDA with the designation “organic.”


One red flag for a label: vague CBD sourcing or no mention of CBD at all. Watch out for “hemp extract” or “hemp oil.” By using these phrases, the manufacturer is deflecting any claim to deliver actual CBD. Amazon.com is loaded with low-quality “hemp oil” products that make medical claims but contain no CBD.


Other Ingredients

  • Beyond raw CBD oil or CBD isolate, most CBD products are going to come with other ingredients. Gummies will commonly contain glycerin, colors, and flavors. Tinctures often come mixed with some other oil, spirits, or glycerin. Scrutinize other ingredients for quality, purity, and the presence of potential allergens.


Warning labels

  • CBD has drug interactions and is not for everyone. Read and heed common sense warnings and disclaimers. It’s important to remember that CBD, like other nutraceuticals, can interact with medications. CBD isn’t effective in treating all types of pain—for that reason, it’s important to understand your pain: does it worsen with the weather, cause swelling, or is it persistent and stabbing? If you feel that you experience inflammatory or neuropathic pain, talk to your doctor. CBD supplementation could be right for you. For more information on potential harmful or helpful drug interactions please go to this link: https://www.leafly.com/news/health/cannabis-cannabinoids-drug-interactions 

Certification

  • A third-party certification attests to the accuracy of the manufacturer’s label claims. Testing for adult-use and medical cannabis is a legally mandated form of third-party certification. One popular type of third-party certification is a Certificate of Analysis (COA) from a cannabis testing lab. Lab quality varies, however. Beware of recycled, old COAs attached to current inventory.


Whats the right dose of CBD?

Your perfect CBD dose depends on a few different factors, including your individual biology, the delivery method, and the specific nature of your symptoms. There is no ideal, one-size-fits-all dose with CBD. Your perfect CBD dose depends on a few different factors, including your individual biology, the delivery method, and the specific nature of your symptoms. For example, high doses of CBD (upward of 600mg daily) seem to be more effective for conditions like epilepsy, whereas low doses are potentially effective for anxiety.


Research is beginning to show that there’s a sweet spot when it comes to dosing cannabinoids like CBD: Consume too much or too little, and you may feel limited relief or side effects. More research is needed to develop specific guidelines around CBD dosing for different medical conditions. Until then—if you’re using CBD oils, edibles, or other products to treat symptoms like anxiety, stress, pain, or insomnia—consider starting with a low dose of CBD (around 5mg) and slowly increasing until you’ve found the optimal dose for you.



For more information and the resources I used please visit these links:

https://fivethirtyeight.com/features/you-can-get-cannabis-in-your-coffee-but-does-is-it-really-do-anything/

https://www.leafly.com/news/cannabis-101/what-is-cbd

https://www.nap.edu/catalog/24625/the-health-effects-of-cannabis-and-cannabinoids-the-current-state

https://clinicaltrials.gov/ct2/results?cond=&term=Cannabidiol&cntry=&state=&city=&dist=

https://pubmed.ncbi.nlm.nih.gov/22483680/

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Recipes
Cannabis Infused Pumpkin Mac and Cheese

Cook Time: 20 min |  Total Time: 20 Min |  Servings: 6


Ingredients

  • 1 lb elbow macaroni pasta
  • 3 tablespoons unsalted butter
  • 2 tablespoons all-purpose flour
  • 2 cups low-fat milk
  • 2 cups mild cheddar cheese shredded (for best results, don't use bagged kind already shredded)
  • 1 cup canned pumpkin puree
  • 1/2 teaspoon Kosher salt
  • Optional toppings: Whole wheat bread crumbs parmesan cheese

Instructions

  1. In a large pot or dutch oven, bring salted water to a boil. Cook macaroni according to package directions. Drain and set aside.
  2. Meanwhile, in a medium saucepan melt butter over medium low heat, stirring frequently. Stir in flour until mixed in and thickens. Slowly add milk, whisking continuously while doing so. Break up any clumps that form and work them into the sauce.
  3. Once sauce is smooth, add cheddar cheese and pumpkin to milk and butter mixture. Increase heat to medium and continue using whisk until cheese is melted completely.
  4. Pour cheese sauce over pasta and mix until pasta is evenly coated with cheese.
  5. Serve with a sprinkle of whole wheat bread crumbs and parmesan cheese on top.

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Recipes
CBD Trash Cookies

I'm a sucker for a good chocolate chip cookie, but everytime I make a homemade edible I always wish I didn't taste that stereotypical "weedy" flavor. That's where the "Trash" part of this cookie comes in. Adding in something salty and crunchy to a sweet cookie adds a difference in flavor that masks the flavors we don't want. This recipe is formulated specifically for the CBD distillate syringes at a certain concentration; if you do make a substitution, please exercise caution. It's always better to make them too weak than too strong because these cookies are *that* good, it'd be a shame to only eat one.

There are a few little notes in this recipe to ensure you get perfect cookies every single time- I recommend a cookie scoop like one out of this set to get going. It's a good tool to have if you're interested in making your own edibles.

Bake Time: 8-10 Min |  Prep Time: 15 min |  Makes 24 (1.5 Tablespoon) Cookies or 16 (2.5 Tablespoon) Cookies

Ingredients

  • 2 1/4 cups all-purpose flour
  • 1 teaspoon baking soda
  • 1 teaspoon salt
  • 1 cup (2 sticks) butter, softened
  • 1 Bloom Montana CBD Distillate Syringe (made into the edible form, not a cartridge and roughly testing around 50-60% CBD)
  • 3/4 cup granulated sugar
  • 3/4 cup packed brown sugar
  • 1 teaspoon vanilla extract
  • 2 large eggs
  • 2 cups (12-ounce package) Semi-Sweet Chocolate Morsels
  • 1/2 cup chopped nuts
  • 1 cup pretzels or thick kettle-cooked potato chips, broken up a bit- not crushed
  • Sprinkles are optional, but fun

Instructions

  1. Preheat oven to 375° F.
  1. Combine flour, baking soda and salt in small bowl. Beat butter, granulated sugar, brown sugar, CBD distillate syringe and vanilla extract in large mixer bowl until creamy. About 5 minutes. You really want the mixture to have lightened significantly and fluffed up.
  1. Add eggs, one at a time, beating well after each addition. Gradually beat in flour mixture. It should still look a little floury- not entirely mixed.
  1. Stir in morsels, nuts and pretzels. This can be done by hand. If you stir too much at this point it will lead to a significantly chewier cookie. Drop by rounded tablespoon onto ungreased baking sheets. Consistency is key, you want every cookie to be even so you don't have different concentrations in your cookies. Spring loaded cookie scoops are great for this purpose and they can be found in most every box store and on amazon.
  1. Place baking sheet into a freezer for about 10 minutes. This gives the butter a chance to keep the cookies soft and not spread too much. If you like a chewy crunchy cookie, feel free to skip this step.
  1. Bake for 8-10 minutes or until a light golden brown. Cool on baking sheets for 2 minutes; remove to wire racks to cool completely.
  1. PAN COOKIE VARIATION: Preheat oven to 350° F. Grease 15 x 10-inch jelly-roll pan. Prepare dough as above. Spread into prepared pan. Bake for 20 to 25 minutes or until golden brown. Cool in pan on wire rack. Makes 2 dozen bars.


May be stored in refrigerator for up to 1 week or in freezer for up to 8 weeks. 


FOR HIGH ALTITUDE BAKING (5,200 feet): Increase flour to 2 1/2 cups. Add 2 teaspoons water with flour and reduce both granulated sugar and brown sugar to 2/3 cup each. Bake drop cookies for 8 to 10 minutes and pan cookie for 17 to 19 minutes.

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Life in Bloom
The Do's and Dont's of Edible Dosing

Every person has a unique internal physiologic environment and can therefore experience different results with various medications. One person’s response to a dose of edible cannabis can vary significantly from the next, even more so than other medications or herbs. Why?

Several factors are involved, including previous history of cannabis use, gastrointestinal factors, and the function/sensitivity of one’s endocannabinoid system. 

Once you go above 100 mg and into extremely high dosages such as 150 mg, 200 mg, or even 500 mg marijuana edibles, the risk of negative effects associated with the idea of overconsuming cannabis—such as nausea and paranoia—increase, even for consumers who may have very high tolerances.


There are a few things to consider that may alter your cannabis experience:


  • THC has biphasic properties, which means at one dose it might have one effect (relieves stress) but one larger can cause the opposite (increased feelings of stress). 
  • Taking THC edibles on an empty stomach can cause your dose to be absorbed faster with a more intense onset. A meal rich in fat can cause you to absorb more THC than usual. 
  • If you take your regular dose outside of your normal routine, it can cause a completely different experience. 
  • If you ever become uncomfortable from overconsumption try laying down, closing your eyes, and take deep slow breaths. You can also try watching a funny or comforting movie.
  • If you feel like you are experiencing trouble breathing or heart-related problems, you should seek medical attention.


How many mg of edibles should you eat?


The ideal edibles dose depends on a lot of things, including tolerance, individual body chemistry, and the experience you’re looking for. But there are some basic guidelines that can help you find the right dose of marijuana edibles, which are measured in milligrams (mg).


1 – 2.5 mg THC edibles

Effects include: Mild relief of symptoms like pain, stress, and anxiety; increased focus and creativity.

Good for: First-time consumers or regular consumers looking to microdose.

2.5 – 15 mg THC edibles

Effects include: Stronger relief of pain and anxiety symptoms; euphoria; impaired coordination and perception.

Good for: Standard recreational use; persistent symptoms not addressed by smaller doses; people looking for a good night’s sleep.

30 – 50 mg THC edibles

Effects include: Strong euphoric effects; significantly impaired coordination and perception.

Good for: High tolerance THC consumers; consumers whose GI systems don’t absorb cannabinoids well.

50 – 100 mg THC edibles

Effects include: Seriously impaired coordination and perception; possible unpleasant side effects including nausea, pain, and increased heart rate.

Good for: Experienced, high-tolerance THC consumers; patients living with inflammatory disorders, cancer, and other serious conditions.


How long does it take to feel an effect from edibles?

The most common mistake in cannabis dosing occurs when a person doesn’t feel any effect from an edible after one hour and decides to take another dose; two hours later, both doses come through and the individual experiences the unpleasant effects of a cannabis overconsumption.


Adding CBD to THC can enhance the medical benefits of marijuana edibles, such as pain or anxiety relief, while decreasing the adverse effects, such as impairment and elevated heart rate. CBD partially blocks the intoxicating effects of THC, so consumers who wish to experience the medical benefits of cannabis without as much impairment can best achieve this with products that contain both CBD and THC. It’s important for consumers to know the contents of each of these components and the ratio of CBD to THC.

Products with a CBD:THC ratio of 1:1 are powerfully therapeutic and produce less impairment than a THC-dominant product. Excessive doses of these products can still produce classic cannabis overconsumption symptoms.


Tips for relieving overconsumption of edibles

  • Be in a calm, safe environment and have gentle reassurance that everything will be OK is the primary treatment.
  • Stay hydrated.
  • A large 50-200mg dose of CBD (without significant amounts of THC) can act as a partial antidote. Lemon oil, found predominantly in the rind and in lower amounts in the juice, has also been used historically for this purpose. Grate a tablespoon of lemon zest and chew it up before swallowing.
  • Most people do not need emergency medical care unless they have pre-existing heart disease or another serious medical condition. For ongoing vomiting and diarrhea, intravenous rehydration may be necessary.



References:

https://bakedbros.com/blogs/news/edible-dosage-mg-chart

https://healer.com/cannabis-edibles-dosing-chart-find-the-right-dose/


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Life in Bloom
October Strain of the Month- Lemon Walker

Lemon Walker is a Sativa strain with award-winning parents- Lemon Skunk and Skywalker OG. Most consumers have liked Lemon Walker, because it has offered an energetic and creative state of mind that allowed them to stay focused and left their body pain-free. Users have suggested to use Lemon Walker to help ease symptoms of ADD, ADHD, PTSD, depression, stress, chronic fatigue, chronic pain and migraines.

The buds are lemon and citrus-scented, but the flavor is all the way Kush, with slightly fruity undertones. Lemon Walker is great for stimulating appetites and helps with concentration. She delivers a potent, cerebral buzz that has an uplifting, mood-enhancing effect.


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